Comparison of different laparoscopic treatments for upper urinary tract urothelial carcinoma
10.3969/j.issn.1009-8291.2024.07.007
- VernacularTitle:不同腹腔镜术式治疗上尿路尿路上皮癌的临床疗效比较
- Author:
Meng ZHU
1
;
Junfei GU
1
;
Yuepeng LIU
1
;
Zihao LI
1
;
Chao MA
1
;
Lixin REN
1
Author Information
1. Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
- Publication Type:Journal Article
- Keywords:
peritoneolaparoscopic single position nephreteral total length resection;
posterior laparoscopic subabdominal incision technique;
upper tract urothelial carcinoma
- From:
Journal of Modern Urology
2024;29(7):597-601
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To compare the clinical efficacy of peritoneolaparoscopic single position nephreteral total length resection (PSPNTLR) and posterior laparoscopic subabdominal incision technique (PLSIT) in the treatment of upper urothelial carcinoma (UTUC). 【Methods】 A total of 82 UTUC patients treated in our hospital during Jan.2018 and Feb.2021 were divided into the observation group (n=41, treated with PSPNTLR) and control group (n=41, treated with PLSIT) according to the random number table method.Perioperative indicators, pain degree, inflammatory factors, bladder recurrence and distant metastasis were compared between the two groups. 【Results】 The operation time \[(122.15±15.14) min vs.(160.88±17.26) min\], hospitalization time \[(10.07±2.14) d vs.(12.22±3.13) d\] and postoperative exhaust time \[(1.46±0.57) d vs.(3.10±0.88) d\] were significantly shorter, the intraoperative blood loss \[(42.85±4.88) mL vs. (78.22±8.17) mL\] and drainage volume \[(53.61±9.74) mL vs.(81.56±11.06) mL\] were significantly less in the observation group than in the control group (P<0.05).The visual analogue score (VAS) of the observation group at 6, 12 and 24 h after operation was significantly lower than that of the control group (P<0.05).The levels of interleukin-6 (IL-6) and C-reactive protein (CRP) were increased in both groups one day after surgery, but the indexes were increased more significantly in the control group (P<0.05).During the 2-year follow-up after surgery, there were no statistical difference in bladder recurrence (12.20% vs.14.63%) and distant metastasis (9.76% vs.4.88%) between the two groups (P>0.05). 【Conclusion】 Both PSPNTLR and PLSIT have good therapeutic safety, but PSPNTLR is more effective in improving perioperative indicators, reducing postoperative pain, and inhibiting inflammatory factors.
