Herbal Textual Research， Quality Evaluation and Phase Analysis of Stalactitum
10.13422/j.cnki.syfjx.20240561
- VernacularTitle:钟乳石的本草考证、品质评价及物相分析
- Author:
Jianxiong WEI
1
;
Yuan SUN
1
;
Daihong CHEN
1
;
Youshao WANG
1
;
Min ZHANG
1
;
Juan LI
1
Author Information
1. School of Pharmacy，Hubei University of Chinese Medicine，Wuhan 430065，China
- Publication Type:Journal Article
- Keywords:
Stalactitum;
quality evaluation;
herbal textual research;
calcium carbonate;
calcite;
X-ray diffraction（XRD）;
physical phase analysis
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2024;30(21):203-211
- CountryChina
- Language:Chinese
-
Abstract:
Aiming to provide the foundation for the quality evaluation， in this paper， a comprehensive examination of historical materia medica， medical books and modern literature was conducted to systematically compile and verify the naming， origin and quality of Stalactitum， combined with the phase analysis of 20 batches of samples. The investigation indicates that before the Qing dynasty， Stalactitum was often referred to as Shizhongru， and there are other aliases such as Xuzhong， Xiashi and Huangshisha. In addition， there are some homologous mixed names such as Konggongnie， Yinnie， Ruchuang， Ruhua， but Zhongrushi is more commonly used. The descriptions of Stalactitum in ancient materia medica align with modern carbonate mineral calcite， slightly conical or cylindrical in shape， mostly white， grey and yellow in colour， often with a hole in the centre， and has a calcium carbonate content of 95% or more. Historical quality assessments include phrases such as gooseneck tube， cicada wing， bright and white， and brightness， the gloss is the most crucial feature. Modern evaluations encompass features like white color， hollow interior， brightness， multiple layers of patterns， and cross-sectional mask spark-like luminosity. Under the scanning electron microscope， Stalactitum showed obvious layered characteristics and uniform particle size， while the OS Balanophylliae was irregular. By comparing the characteristics and micro-features of Stalactitum from different batches， along with X-ray diffraction（XRD） and determination of calcium carbonate， the phase composition of different batches of Stalactitum was roughly similar， all of them were dominated by calcite， with magnesium calcite as an additional ingredient， the content of CaCO3 was relatively higher for those with brightness and a lot of spark-like luminosity， which were key features of its quality evaluation， the white color could be used as a quality reference， and layered patterns and papillary bulge could be used as a medicinal material identification feature， which were basically consistent with the results of herbal textual research. This study can provide a reference for the quality evaluation of mineral medicines， and can better guide their clinical use and rational utilization of resources.
