Successful Anticoagulation Therapy for Antiphospholipid Syndrome with Mobile Aortic Thrombi.
10.5758/vsi.2016.32.4.186
- Author:
Hyun Oh PARK
1
;
Seong Ho MOON
;
Jong Woo KIM
;
Joung Hun BYUN
;
Sung Hwan KIM
;
Jun Ho YANG
;
Chung Eun LEE
;
Jong Duk KIM
Author Information
1. Department of Thoracic and Cardiovascular Surgery, College of Medicine and Institute of Health Sciences, Gyeongsang National University Changwon Hospital, Changwon, Korea. hoya_m@naver.com
- Publication Type:Case Report
- Keywords:
Aorta;
Thrombosis;
Antiphospholipid syndrome
- MeSH:
Angiography;
Antibodies;
Antiphospholipid Syndrome*;
Aorta;
Aorta, Thoracic;
Brain;
Echocardiography, Transesophageal;
Emergency Service, Hospital;
Glycoproteins;
Humans;
Infarction;
Magnetic Resonance Imaging;
Male;
Middle Aged;
Paresis;
Thrombophilia;
Thrombosis
- From:Vascular Specialist International
2016;32(4):186-189
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hypercoagulable states have been associated with aortic thrombosis. Antiphospholipid syndrome (APS) is one of the commonest types of acquired thrombophilia. We report the case of successful anticoagulation management in an APS patient with mobile thrombi within the aorta. A 58-year-old male patient presented to the emergency department (ED) with right-sided hemiparesis. His first symptoms were noted approximately 12–16 hours before presentation to the ED. Magnetic resonance imaging of the brain showed acute embolic infarction of the left frontal and parietotemporal lobes. Transesophageal echocardiography (TEE) and computed tomography angiography (CTA) demonstrated mobile thrombi attached to the wall of the ascending aorta and aortic arch. The patient was diagnosed with APS based on positivity of anti-beta-2 glycoprotein 1 antibodies, and was initiated on anticoagulation therapy. Repeated TEE and CTA revealed complete resolution of the thrombi after 12 days of treatment; the patient was discharged well.
