Absorption and Half-Life.
10.12793/tcp.2016.24.4.157
- Author:
Nick HOLFORD
1
Author Information
1. Department of Pharmacology & Clinical Pharmacology, University of Auckland, Auckland, New Zealand. n.holford@auckland.ac.nz
- Publication Type:Review
- Keywords:
absorption;
half-life;
pharmacokinetics;
clinical pharmacology
- MeSH:
Absorption*;
Drug Therapy;
Half-Life*;
Pharmacokinetics;
Pharmacology, Clinical
- From:Translational and Clinical Pharmacology
2016;24(4):157-160
- CountryRepublic of Korea
- Language:English
-
Abstract:
This tutorial deals with basic concepts of absorption processes and links previous tutorials on clearance and volume of distribution to introduce the concept of half-life. The time course of both absorption and elimination are commonly described using a half-life. Half-life can also be used to describe drug accumulation. Understanding the principles underlying the time course of absorption and elimination are essential in pharmacotherapy and clinical pharmacology.
