Anti-Inflammatory Herbal Extracts and Their Drug Discovery Perspective in Atopic Dermatitis
10.4062/biomolther.2023.102
- Author:
Jae-Won LEE
1
;
Eun-Nam KIM
;
Gil-Saeng JEONG
Author Information
1. Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 28116, Republic of Korea
- Publication Type:Review
- From:Biomolecules & Therapeutics
2024;32(1):25-37
- CountryRepublic of Korea
- Language:English
-
Abstract:
Atopic dermatitis (AD) is an allergic disorder characterized by skin inflammation. It is well known that the activation of various inflammatory cells and the generation of inflammatory molecules are closely linked to the development of AD. There is accumulating evidence demonstrating the beneficial effects of herbal extracts (HEs) on the regulation of inflammatory response in both in vitro and in vivo studies of AD. This review summarizes the anti-atopic effects of HEs and its associated underlying mechanisms, with a brief introduction of in vitro and in vivo experiment models of AD based on previous and recent studies. Thus, this review confirms the utility of HEs for AD therapy.
