Role of inflammatory cytokines in disorder of glucose metabolism in patients with liver cirrhosis
- VernacularTitle:炎症细胞因子在肝硬化患者糖代谢紊乱中的作用
- Author:
Yunchong WU
1
;
Yanyan YANG
1
;
Chuan LI
1
;
Xiaohuan WU
1
;
Shide LIN
1
Author Information
- Publication Type:Review
- Keywords: Liver Cirrhosis; Insulin Resistance; Inflammation; Cytokines
- From: Journal of Clinical Hepatology 2024;40(9):1886-1890
- CountryChina
- Language:Chinese
- Abstract: In recent years， there has been a deeper understanding of the role and mechanisms of common inflammatory cytokines in the development and progression of liver cirrhosis， such as interleukin-1β， interleukin-6， interleukin-10， interleukin-17， tumor necrosis factor-α， interferon-γ， and C-reactive protein， and significant achievements have also been made in the research on the association of these inflammatory cytokines with disorder of glucose metabolism and pancreatic islet dysfunction. This article reviews the role of inflammatory cytokines in patients with liver cirrhosis and their impact on disorder of glucose metabolism and pancreatic islet dysfunction， in order to provide a theoretical basis for clarifying the pathogenesis of hepatogenous diabetes and performing the clinical management of the disease.
