Quantitative Analysis of Tissue Injury after Minimally Invasive Total Hip Arthroplasty.
10.4055/cios.2014.6.3.279
- Author:
Sangjoon KWAK
1
;
Youngsoo CHUN
;
Kihyung RHYU
;
Jaeryong CHA
;
Yoonje CHO
Author Information
1. Department of Orthopaedic Surgery, Kyung Hee University School of Medicine, Seoul, Korea. yjcho@khmc.ac.kr
- Publication Type:Original Article ; Comparative Study
- Keywords:
Total hip arthroplasty;
Minimally invasive surgery;
Muscle enzyme
- MeSH:
Adult;
Aged;
Aged, 80 and over;
Arthroplasty, Replacement, Hip/*adverse effects;
Biological Markers/blood;
Creatine Kinase/blood;
Female;
Fructose-Bisphosphate Aldolase/blood;
Humans;
Interleukin 1 Receptor Antagonist Protein/blood;
Interleukin-10/blood;
Interleukin-6/blood;
Interleukin-8/blood;
Male;
Middle Aged;
Minimally Invasive Surgical Procedures/adverse effects;
Soft Tissue Injuries/*blood/etiology
- From:Clinics in Orthopedic Surgery
2014;6(3):279-284
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: We intended to clarify the hypothesis that minimally invasive total hip arthroplasty (MI-THA) leads to less tissue damage and inflammatory response than does conventional total hip arthroplasty (C-THA). METHODS: We performed 30 cases of THA between September 2005 and May 2006 and evaluated these cases prospectively. We chose 15 MI-THA cases for the study group and another 15 C-THA cases for the control group. We checked skeletal muscle marker enzymes, such as serum creatinine kinase and aldolase, the pro-inflammatory cytokines, interleukin (IL)-6 and 8, and the anti-inflammatory cytokines, IL-10 and IL-1 receptor antagonist (ra) the day before surgery and at postoperative days 1, 7, and 14. RESULTS: On postoperative days 1 and 3, the study group showed significantly lower serum creatinine kinase, IL-6, IL-10, and IL-1ra values than those in the control group. Additionally, IL-8 was significantly lower on day 7 after surgery. CONCLUSIONS: These data show that MI-THA decreased the release of muscle marker enzymes due to tissue damage immediately after surgery and minimized the inflammatory response related to the surgery during the early postoperative period.
