Diagnostic Strategies and Clinical Practice of Bone Marrow Metastases from Ewing Sarcoma
10.3971/j.issn.1000-8578.2024.24.0106
- VernacularTitle:尤因肉瘤骨髓转移的诊断策略与临床实践
- Author:
Wanru WANG
1
;
Yuhong ZHOU
;
Qin WANG
;
Jiaqi XIE
;
Baorui LIU
;
Rutian LI
Author Information
1. 210023 江苏,南京中医药大学鼓楼临床医学院
- Keywords:
Ewing sarcoma;
Bone marrow metastases;
Diagnostic;
Clinical practice
- From:
Cancer Research on Prevention and Treatment
2024;51(9):794-798
- CountryChina
- Language:Chinese
-
Abstract:
Ewing sarcoma(EWS)is an invasive and primary bone tumor with a high incidence in children and adolescents.The presence and extent of metastases at the time of diagnosis remains the most important prognostic factor in determining a patient's prognosis.Up now,considerable ambiguity exists regarding the optimal modality for detecting bone marrow metastases.Bone marrow biopsy and/or aspiration(BMBA)is the gold standard for determining bone marrow metastases.This invasive and painful procedure may be amenable to being replaced by 18F-FDG PET/CT because of its high sensitivity in detecting EWS bone and extraosseous metastases.This review provides an overview of the current literature,concludes that there is no longer a systematic consensus on the implementation of BMAB criteria for the diagnosis of bone marrow metastases in EWS,and summarizes the current practical strategies and clinical practices for the diagnosis of EWS bone marrow metastases accordingly.
