Relationship Between Ruminococcus and Colorectal Cancer and Its Anti-Cancer Mechanism
10.3971/j.issn.1000-8578.2024.24.0235
- VernacularTitle:瘤胃球菌与结直肠癌的关系及其影响胃肠道的机制探讨
- Author:
Zhiyang CAI
1
;
Heiying JIN
;
Chunxia ZHANG
;
Lei SHU
;
Yaoan LIU
Author Information
1. 210017 南京,南京中医药大学第二附属医院(江苏省第二中医院)肛肠外科
- Keywords:
Colorectal cancer;
Intestinal flora;
Ruminococcus;
R.bromii;
R.callidus;
Butyrate
- From:
Cancer Research on Prevention and Treatment
2024;51(9):789-793
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies found that the intestinal flora is involved in the occurrence and development of CRC.In particular,Ruminococcus shows a decreased abundance in patients with CRC and can affect gastrointestinal health through cross-feeding and promoting butyrate production.Although the research on Ruminococcus is gradually increasing,no unified understanding of its influence on the occurrence and development of CRC has been established.This work summarizes the relationship of Ruminococcus with CRC and its possible anticancer mechanism to provide a theoretical basis for the further exploration of biological prevention and treatment of CRC in the future.
