Relationship Between Ruminococcus and Colorectal Cancer and Its Anti-Cancer Mechanism
10.3971/j.issn.1000-8578.2024.24.0235
- VernacularTitle:瘤胃球菌与结直肠癌的关系及其影响胃肠道的机制探讨
- Author:
Zhiyang CAI
1
;
Heiying JIN
1
;
Chunxia ZHANG
1
;
Lei SHU
1
;
Yaoan LIU
1
Author Information
1. Department of Anorectal Surgery, Jiangsu Provincial Second Chinese Medicine Hospital (The Second Affiliated Hospital of Nanjing University of Chinese Medicine), Nanjing 210017, China.
- Publication Type:REVIEWS
- Keywords:
Colorectal cancer;
Intestinal flora;
Ruminococcus;
R.bromii;
R.callidus;
Butyrate
- From:
Cancer Research on Prevention and Treatment
2024;51(9):789-793
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies found that the intestinal flora is involved in the occurrence and development of CRC. In particular, Ruminococcus shows a decreased abundance in patients with CRC and can affect gastrointestinal health through cross-feeding and promoting butyrate production. Although the research on Ruminococcus is gradually increasing, no unified understanding of its influence on the occurrence and development of CRC has been established. This work summarizes the relationship of Ruminococcus with CRC and its possible anticancer mechanism to provide a theoretical basis for the further exploration of biological prevention and treatment of CRC in the future.
