Investigation of human parvovirus B19 infection in college students
10.13303/j.cjbt.issn.1004-549x.2024.08.012
- VernacularTitle:大学生群体人细小病毒B19感染状况调查
- Author:
Zhiyong WANG
1
;
Jinhua AN
;
Jingru CUI
;
Yanfei LI
;
Kaiye LI
;
Min HE
Author Information
1. 长春市中心血站,吉林 长春 130031
- Keywords:
human parvovirus B19;
college students;
blood donors;
ELISA;
PCR
- From:
Chinese Journal of Blood Transfusion
2024;37(8):914-917,945
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence of human parvovirus B19(B19V)infection among college students,so as to provide reference for the development of blood donor screening strategies and blood supply policies.Meth-ods From March 2023 to February 2024,blood donor samples from college students in Changchun were retrospectively an-alyzed using the principle of random numbers,with samples taken 1 to 3 days per month.B19V IgG/IgM were detected by ELISA,and B19V DNA and viral load were measured by real-time quantitative PCR.Results Among 1 456 blood donor samples from college students,the positive rates for B19V IgG,IgM and DNA were 11.54%,0.34%and 2.68%,respec-tively.The viral load in 39 B19V DNA-positive samples ranged from 5.60×102 IU/mL to 9.10×106 IU/mL,with 28 samples(1.92%)having a viral load above 104 IU/mL.There were 11 samples(0.76%)that were positive for B19V DNA but neg-ative for IgG/IgM.Conclusion The college students have a low prevalence of past B19V infection,but a higher risk of in-fections and a higer proportion of acute infections with high viral loads in individuals who are]B19V IgG negative,presenting a risk of transmission through blood transfusion.Targeted blood safety monitoring is necessary for college students to track the prevalence of B19V DNA.
