Dryness of Atractylodis Rhizoma： A Review
10.13422/j.cnki.syfjx.20240863
- VernacularTitle:苍术燥性的研究进展
- Author:
Ding YAO
1
;
Chang KE
1
;
Songyang YU
1
;
Kang XU
1
;
Yanju LIU
1
;
Linghang QU
1
Author Information
1. School of Pharmacy，Hubei Processing Engineering and Technology Center of Traditional Chinese Medicine，Hubei Shizhen Laboratory，Hubei University of Chinese Medicine，Wuhan 430065，China
- Publication Type:Journal Article
- Keywords:
Atractylodis Rhizoma;
dryness characterization;
Chinese medicine processing;
quality markers;
bran-fried products;
β-eudesmol;
atractylon
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2024;30(19):292-298
- CountryChina
- Language:Chinese
-
Abstract:
Dryness is an important concept in the theory of traditional Chinese medicine， which is closely related to the transformation of the body， etiology and pathogenesis. As one of the medicinal properties of Chinese materia medica， there are various types of Chinese materia medica with dryness. Atractylodis Rhizoma（AR） is a representative medicine with warm and dry properties， which has the function of drying dampness and strengthening the spleen. Due to its strong dryness， it can cause certain adverse reactions. In clinical practice， stir-fried AR with bran is often used as medicine. The dryness of AR is closely related to its efficacy， but the underlying mechanism of the relationship between dryness and efficacy is still unclear. At present， the research on dryness Chinese materia medica has been increasing year by year， but there are still problems such as insufficient systematic research， insufficient in-depth research and lack of research on the mechanism of dryness effect， which limit the breakthrough of the theory of processing for slowing down dryness， and hinder the precise application of dryness Chinese materia medica in clinical practice. Therefore， this article comprehensively reviewed the differences in dryness characterization indicators of different Chinese materia medica by searching domestic and foreign literature， focusing on the relevant research on dryness of AR. A systematic summary and induction were made from the characterization indicators， research techniques of dryness markers， the influence of processing on dryness of AR， and the application mining of dryness of AR. The results showed that the dryness characteristics of AR mainly included the upregulation of macroscopic indicators such as water intake， urine output and whole blood viscosity， as well as energy metabolism indicators， the downregulation of water metabolism indicators， and pathological changes such as submandibular gland acinar atrophy. Based on the changes of dryness and component content of AR after processing， it is determined that the main dryness components of AR may be volatile components such as β-eudesmol and atractylon. Due to its dryness， AR is mainly used to treat diseases such as spleen deficiency， rheumatism and edema. However， the current understanding of the correlation between dryness and efficacy of AR is still insufficient， and there are still many bottlenecks in understanding and explaining its dryness. In the future， systematic evaluation and characterization should be carried out to find the common mechanism of AR exerting dryness and efficacy， providing reference for the rational clinical use.
