Molecular mechanism of traditional Chinese medicine active components in regulating glucose metabolism against cholangiocarcinoma
- VernacularTitle:中药活性成分调控糖代谢抗胆管癌的分子机制
- Author:
Fangyan ZHAO
1
;
Shan LI
;
Xiangqi WANG
;
Yi YIN
Author Information
- Keywords: Bile Duct Neoplasms; Carbohydrate Metabolism; Traditional Chinese Drugs; Molecular Mechanisms of Pharmacological Action(TCD)
- From: Journal of Clinical Hepatology 2024;40(8):1704-1708
- CountryChina
- Language:Chinese
- Abstract: Cholangiocarcinoma is a highly heterogeneous tumor with an insidious onset,severe conditions,a high degree of malignancy,and an extremely poor prognosis.Glucose is a major energy source for the proliferation and metastasis of cholangiocarcinoma,and the glucose metabolism pathway of cholangiocarcinoma cells will be re-edited in the process of rapid proliferation to produce a large amount of energy for their own needs.Traditional Chinese medicine has unique advantages in the treatment of cholangiocarcinoma,and studies have shown that the active components of traditional Chinese medicine can inhibit the development and progression of cholangiocarcinoma by regulating glucose metabolism.This article reviews the characteristics of glucose metabolism in cholangiocarcinoma and the role of the active components of traditional Chinese medicine in regulating glucose metabolism against cholangiocarcinoma,in order to provide new ideas for the treatment of cholangiocarcinoma.
