Association of lipid metabolism reprogramming with the development and progression of primary liver cancer

VernacularTitle:脂代谢重编程与原发性肝癌发生发展的关系
Author: Feiyan LI ¹ ; Minggang WANG ² ; Dewen MAO ³ ; Riyun ZHANG ¹ ; Na WANG ³ ; Yinbing LUO ¹ ; Xiaoping LIU ¹ ; Yupei LIN ¹
Author Information

1. Graduate School， Guangxi University of Chinese Medicine， Nanning 530200， China
2. Department of Scientific Research， The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning 530023， China
3. Department of Hepatology， The First Affiliated Hospital of Guangxi University of Chinese Medicine， Nanning 530023， China
Publication Type:Review
Keywords: Liver Neoplasms; Lipid Metabolism; Metabolic Reprogramming
From: Journal of Clinical Hepatology 2024;40(8):1688-1692
CountryChina
Language:Chinese
Abstract: Lipid metabolism， as the basis of life maintenance， is a prerequisite for cell survival， and lipid homeostasis can rapidly respond to metabolic changes in a coordinated manner. In cancers， there is an increase in lipid metabolism in cancer cells to meet the requirements for plasma membrane synthesis and energy production. Abnormal lipid metabolism plays an important role in the progression of primary liver cancer. This article reviews the association between abnormal lipid metabolism and primary liver cancer， in order to find targets for the prevention and treatment of primary liver cancer.