Update on antibiotic resistance of common pathogenical bacteria isolated in Hue University of Medicine and Pharmacy Hospital

Dinh Binh Tran; Viet Quynh Tram Ngo; Thi Bao Chi LE; Thi Chau Anh Nguyen; Hoang Bach Nguyen; Van Bao Thang Phan; Thi Khanh Linh Nguyen; Nu Xuan Thanh LE; Thi Dang Khoa Nguyen; Thi Tuyen Nguyen; Thi Thuy Ung; Thi Hai Dinh; Thi Ngoc Mai Duong; Minh Ngoc Hoang; Viet Tu Nguyen; Le Bich Ngoc Hoang; Tuan Khoi Tran; Doan Hieu Tran; Thi Tuyet Ngoc Tran; Van An LE

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Update on antibiotic resistance of common pathogenical bacteria isolated in Hue University of Medicine and Pharmacy Hospital

VernacularTitle:Cập nhật tính đề kháng kháng sinh của các loại vi khuẩn phân lập được tại Bệnh viện Trường Đại học Y - Dược Huế từ năm 2020 - 2022
Author: Dinh Binh TRAN ^{1
,

2} ; Viet Quynh Tram NGO ¹ ; Thi Bao Chi LE ¹ ; Thi Chau Anh NGUYEN ¹ ; Hoang Bach NGUYEN ¹ ; Van Bao Thang PHAN ¹ ; Thi Khanh Linh NGUYEN ¹ ; Nu Xuan Thanh LE ¹ ; Thi Dang Khoa NGUYEN ¹ ; Thi Tuyen NGUYEN ¹ ; Thi Thuy UNG ¹ ; Thi Hai DINH ¹ ; Thi Ngoc Mai DUONG ¹ ; Minh Ngoc HOANG ¹ ; Viet Tu NGUYEN ² ; Le Bich Ngoc HOANG ² ; Tuan Khoi TRAN ² ; Doan Hieu TRAN ² ; Thi Tuyet Ngoc TRAN ³ ; Van An LE ¹
Author Information

1. Microbiology, Hue University of Medicine and Pharmacy Hospital
2. Dept of Infectious Control, Hue University of Medicine and Pharmacy Hospital
3. Biomedicine Institute, Hue University of Medicine and Pharmacy, Hue University
Keywords: Hue University of Medicine and Pharmacy Hospital (Hue UMP Hospital); antimicrobial resistance; antimicrobial agents; bacterial infections
From: Hue Journal of Medicine and Pharmacy 2023;13(7):66-74
CountryViet Nam
Language:Vietnamese
Abstract: Backgroud: The aim of this study is to update on antibiotic resistance of common pathogenical bacteria isolated in Hue University of Medicine and Pharmacy Hospital (Hue UMP Hospital). Methodology: Use of the agar disk diffusion method to test the susceptibility to antimicrobial agents of 3709 bacterial strains from infected patients hospitalized in Hue UMP Hospital in 2020 - 2022. Results: Among 3709 strains of pathogenical bacteria isolated, S.aureus was found with the rate of 29.9%, followed by E. coli (24.5%), Pseudomonas aeruginasa (17.8%), Enterococcus spp. (11.8%), Klebsiella spp (9.7%) and Acinetobacter spp (4.1%). The proportion of bacterial isolates has changed, but Staphylococcus aureus is still highest rate. S.aureus is resistant to many antibiotics, but MRSA strains have decreased significantly, from 73.3% in 2020 to 62.5% in 2022. Pseudomonas aeruginosa was resistant to some of the group A recommended antibiotics such as ceftazidime, piperacillin-tazobactam with the rate of 56.6% and 48.7%. The percentage of E. coli with ESBL strains (+) was at 28.2% - 30.3%. Enterococus spp strains are still sensitive to vancomycin (83.1% - 91.9%). The rate of Klebsiella ESBL (+) is only 6.9% to 8.2%. The strains of Acinetobacter spp were highly resistant to Piperacillin (100%) and Ceftriaxone (96.5%) but they are still sensitive to imipenems 70 - 71%, highly sensitive to Doxycillin (95.2%) and Cefotaxime (88.4%). Conclusion: Many bacterial strains are resistant to many commonly antibiotics. Providing timely, regular, and effective management of antibiotic resistance patterns for common pathogenic bacteria in hospitals, will help reduce the risk of bacterial resistance.