Triterpenoids isolated from the aerial parts of Buxus latistyla Gagnep.

Author: Quoc Hung VO ¹ ; Thuy Vi HUYNH ¹ ; Ngoc Minh Thao DOAN ¹ ; Thi Bich Nguyet HUYNH ¹ ; Thi Minh Hieu NGUYEN ¹ ; Thi Nhat Le DOAN ²
Author Information

1. Faculty of Pharmacy, Hue University of Medicine and Pharmacy, Hue University, Vietnam
2. Faculty of Traditional Medicine, Hue University of Medicine and Pharmacy, Hue University, Vietnam
Keywords: Buxus latistyla; lupeol; lupenone; betulin; 20(29)-lupene-2α; 3α-diol; 20(29)-lupene-2α; 3α; 28-triol.
From: Hue Journal of Medicine and Pharmacy 2023;13(6):72-
CountryViet Nam
Language:English
Abstract: Background: Buxus latistyla Gagnep. (Buxaceae) has been used as a remedy for treating malaria, haemoptysis, amoebic dysentery etc. However, its chemical constituents are still unknown. Thus, the aim of this study was to identify phytochemicals isolated from this plant. Materials and method: Aerial parts of B. latistyla were collected from Quang Tri province. Pure compounds were isolated using the combination of chromatographic methods. Structures of isolated compounds were identified by analyzing spectral data of nuclear magnetic resonance as well as by comparing with reported data. Results & Conclusion: Five triterpenes were isolated and identified including lupeol (1), lupenone (2), betulin (3), 20(29)-lupene-2α,3α-diol (4), 20(29)-lupene-2α,3α,28-triol (5). This is the first report about those phytochemicals of B. latistyla collected in Vietnam.