Discussion on the Treatment of Heart Failure from the Theory of

Yuxuan LI; Wujiao Wang; Peng LI; Yuanyuan Zhang; Xingxing LI; Junyan Xia; Ruli Feng; Dong LI; Qian Lin; Yan LI

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Discussion on the Treatment of Heart Failure from the Theory of "Sweat Pore-Collaterals-Zang and Fu Organs" Based on Mitochondrial Function

VernacularTitle:基于线粒体功能探讨从“玄府-络脉-脏腑”论治心力衰竭
Author: Yuxuan LI ¹ ; Wujiao WANG ² ; Peng LI ¹ ; Yuanyuan ZHANG ¹ ; Xingxing LI ³ ; Junyan XIA ² ; Ruli FENG ² ; Dong LI ⁴ ; Qian LIN ² ; Yan LI ⁴
Author Information

1. Beijing University of Chinese Medicine， Beijing， 100029
2. Dongzhimen Hospital， Beijing University of Chinese Medicine
3. The Affiliated Hospital of Shaanxi University of Chinese Medicine
4. Dongfang Hospital， Beijing University of Chinese Medicine
Publication Type:Journal Article
Keywords: heart failure; mitochondrial; sweat pore; collaterals; zang-fu organs
From: Journal of Traditional Chinese Medicine 2024;65(13):1346-1352
CountryChina
Language:Chinese
Abstract: Mitochondria are the main site of energy metabolism in cardiomyocytes， and at the same time mediate apoptosis and immune response， so mitochondrial dysfunction is closely related to the development of heart failure. Combined with the pathogenesis of mitochondrial dysfunction and heart failure， it is proposed that the mitochondrial function is similar to "sweat pore - collaterals - zang and fu organs"， according to which the treatment of heart failure is based on the theory of "sweat pore - collaterals - zang and fu organs". It is believed that the core mechanism of heart failure is qi deficiency， and qi deficiency leads to the weakness of the sweat pore opening and closing， or even the sweat pore closure， then resulting in qi deficiency and blood stasis， collaterals stagnation fail to flourish， and qi， blood， and body fluids can not infiltrate and nourish zang-fu organs， so that the heart fail to be nourished， and the disease will develop. The treatment should be based on the method of boosting qi and opening sweat pore， using acridity to unblock the collaterals， and invigorating blood and draining water， with medicinal of boosting qi， invigorating blood， and draining water as treatment.