Clinical Evaluation of New Chinese Herbal Medicines for Syndromes： A Preliminary Study on Target Design
10.13288/j.11-2166/r.2024.16.018
- VernacularTitle:证候类中药新药临床评价的靶式设计初探
- Author:
Li ZHANG
1
;
Mengyuan ZHONG
2
;
Yongfa XING
1
;
Duojing LI
2
;
Zheying WU
2
;
Yuhong HUANG
1
Author Information
1. The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine，Tianjin，300250
2. Tianjin University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
new Chinese herbal medicines;
syndromes;
clinical evaluation;
target design;
combination of diseases and syndromes;
correspondence of formulas and syndromes
- From:Journal of Traditional Chinese Medicine
2024;65(16):1730-1733
- CountryChina
- Language:Chinese
-
Abstract:
There are certain limitations in the current clinical evaluation methods and evaluation modes of new Chinese herbal medicines for syndromes， and there is a lack of a clinical evaluation system that meets the characteristics of traditional Chinese medicine （TCM）. Based on the characteristics of TCM "syndrome differentiation and treatment" and "correspondence of formulas and syndromes"， the target design model， hypothesis and its scope of application are proposed on the basis of the combination of diseases and syndromes. On the basis of fully considering the dual factors of diseases and syndromes， we distinguished the "centre of the target"， "middle ring" and "outer ring" through the differences of different signs and symptoms in people with same syndrome， in order to determine the degree of conformity of the syndrome. Then， the population with same syndrome could be analysed according to the "centre of the target"， "middle ring" and "outer ring"， so as to achieve the precise positioning of new Chinese herbal medicines for syndromes， and try to provide research ideas and methods for syndrome differentiation and treatment of TCM and precise intervention.
