Mechanism Evolution of Latent Toxin in Systemic Lupus Erythematosus and Syndrome Differentiation and Treatment
10.13288/j.11-2166/r.2024.16.016
- VernacularTitle:系统性红斑狼疮的伏毒病机演变及辨治
- Author:
Yi ZHANG
1
;
Zhijun XIE
1
;
Lin HUANG
1
;
Qiao WANG
1
;
Haichang LI
1
;
Chengping WEN
1
Author Information
1. Zhejiang Chinese Medical University，Hangzhou，310053
- Publication Type:Journal Article
- Keywords:
systemic lupus erythematosus;
yin-yang toxin;
latent toxin;
evolution of disease mechanism
- From:
Journal of Traditional Chinese Medicine
2024;65(16):1721-1724
- CountryChina
- Language:Chinese
-
Abstract:
It is proposed that the disease mechanism evolution of systemic lupus erythematosus can be summarized into four stages： initial invasion and latency， the pathogenesis remains concealing； latent toxin accumulation， the disease gradually becomes apparent； active toxin begins damaging， the disease manifests aggressively； damage resulting to deficiency， the disease course prolonged. Based on the stages of latent toxin evolution， the syndrome differentiation and treatment of systemic lupus erythematosus can be summarized as follows： during the initial latent stage， characterized by latent dampness and heat stagnation， modified Sanren Decoction （三仁汤） should be used； in the toxin outbreak stage， marked by intense heat toxin， modified Xijiao Dihuang Decoction （犀角地黄汤） combined with modified Qingwen Baidu Decoction （清瘟败毒饮） should be used； during the toxin damage stage， which presents as latent toxin damaging zang-fu organs， modified Qinghao Biejia Decoction （青蒿鳖甲汤） should be used； in the healthy qi deficiency stage， characterized by deficiencies of qi， blood， yin， and yang， modified Xieli Shiquan Ointment （燮理十全膏） should be used.
