Midnight-Noon Ebb-Low Acupuncture by Hour-Prescription of Points Combined with Western Medicine for Parkinson's Disease with Restless Legs Syndrome:A Randomized Controlled Trial
10.13288/j.11-2166/r.2024.16.009
- VernacularTitle:子午流注纳子法针刺联合西药治疗帕金森病合并不宁腿综合征患者30例随机对照试验
- Author:
Xiaodong LI
1
;
Xiuling WU
2
;
Meizhi CAI
2
;
Jia SHI
2
Author Information
1. Tangshan Fengrun Traditional Chinese Medicine Hospital,Tangshan,064000
2. Tangshan Workers' Hospital
- Publication Type:Journal Article
- Keywords:
Parkinson's disease (PD);
restless legs syndrome;
acupuncture;
midnight-noon ebb-low;
hour-prescription of points;
randomized controlled trial
- From:
Journal of Traditional Chinese Medicine
2024;65(16):1681-1686
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the clinical effectiveness of midnight-noon ebb-low acupuncture by hour-prescription of points combined with western medicine for patients of Parkinson's disease with restless legs syndrome. MethodsSixty cases of Parkinson's disease with restless legs syndrome were divided into a control group and a treatment group randomly, with 30 cases in each group. The control group was given conventional western medicine treatment, and the treatment group was given the treatment of the control group with midnight-noon ebb-low acupuncture by hour-prescription of points based on Daling (PC 7), Zhongzhu (TE 3), Yanglingquan (GB 34), Zusanli (ST 36), and Sanyinjiao (SP 6) with perpendicular insertion, and Baihui (GV 20) with oblique insertion to the back,all of them used the manipulation of neutral reinforcement and reduction; Dudu (SP 2) and Taibai (SP 3) acupoints were inserted in accordance with the direction of the meridian travelling when the patients inhaled, and the needle was removed when exhaled; the time of acupuncture manipulation selected as Si time (9 AM-11 AM), the needle stay for 30 mins each time, once a day, 5 times a week, a total of 4 weeks of treatment. The international restless legs severity scale (IRLSS), Pittsburgh sleep quality index (PSQI), Parkinson's disease quality of life questionnaire (PDQ-39), and the International Movement Disorder Society unified Parkinson's disease rating scale part Ⅰ (MDS-UPDRS Ⅰ) were compared before and after the treatment, and the clinical effectiveness of the two groups were compared after the treatment. ResultsIRLSS scores, PSQI scores, PDQ-39 scores and MDS-UPDRS Ⅰ scores decreased in both groups after treatment compared to those before treatment (P<0.05 or P<0.01). After treatment, the total effective rate in the treatment group (83.3%, 25/30) was higher than that in the control group (60%, 18/30) (P<0.05). ConclusionAdding midnight-noon ebb-low acupuncture with hour-prescription of points on conventional western medicine treatment for Parkinson's disease with restless legs syndrome can significantly improve patients' clinical symptoms, sleep quality, quality of life, and enhance clinical effectiveness.