Analysis of viral load in newly reported HIV/AIDS patients in Jiangsu Province in 2019
10.19405/j.cnki.issn1000-1492.2023.09.023
- Author:
Jing Lu
1
;
Zhi Zhang
1
;
Tao Qiu
1
;
Ying Zhou
1
;
Xiaoqin Xu
1
;
Haiyang Hu
1
;
Qi Sun
1
;
Gengfeng Fu
1
Author Information
1. Dept of HIV/STD Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention ,Nanjing 210009
- Publication Type:Journal Article
- Keywords:
HIV/AIDS;
newly reported;
viral load detection
- From:
Acta Universitatis Medicinalis Anhui
2023;58(9):1580-1583
- CountryChina
- Language:Chinese
-
Abstract:
Objective : Viral load is becoming more and more important in prevention of HIV/AIDS. Understanding the baseline of viral load before treatment in newly reported HIV/AIDS patients can provide a basis for AIDS prevention.
Methods :The viral load of newly reported HIV/AIDS patients in Jiangsu province in 2019 was detected by fluorescence quantitative PCR , the differences of viral load under different demographic characteristics were compared , and the factors of high viral load were analyzed.
Results :he mean viral load of 3098 newly reported HIV/AIDS patients in Jiangsu province was 4. 33 ± 1. 05 log/mL , and the proportion of patients with viral load < 5000 copies/mL was 20. 85% (646/3 098) . There were statistically significant differences in viral load among different genders (P < 0. 05) , and male patients had higher viral load. The difference of viral load between HIV⁃infected and AIDS patients was statistically significant (P < 0. 05) , and the viral load value of AIDS patients diagnosed with disease status was relatively high. Unmarried and married spouses were more likely to have higher viral load than divorced or widowed spouses. Higher baseline viral load level was associated with higher rates of virologic failure after antiviral therapy.
Conclusion :The overall viral load of HIV infected /AIDS patients is high , but there is a certain proportion of low viral load , suggesting that follow⁃up of low viral load should be strengthened in AIDS prevention and treatment. Strengthen interventions aimed at men and unmarried or married people with spouses to reduce the risk of transmission.
- Full text:2024081409500547840江苏省2019年新报告HI...IDS患者病毒载量结果分析_卢静.pdf