Eosinophilic Fasciitis as the Initial Manifestation of Graft-Versus-Host Disease.

Author: In Seol YOO ¹ ; Min Kyung KIM ; Seung Tak SONG ; Jin Hyun KIM ; Jin Man KIM ; Deog Yeon JO ; Seong Wook KANG
Author Information

1. Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea. kangsw@cnuh.co.kr
Publication Type:Case Report
Keywords: Eosinophilic fasciitis; Graft-versus-host disease; Allogeneic hematopoietic stem cell transplantation
MeSH: Bone Marrow Transplantation; Eosinophilia; Eosinophils; Fascia; Fasciitis; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Inflammation; Middle Aged; Skin
From:Journal of Rheumatic Diseases 2011;18(1):64-67
CountryRepublic of Korea
Language:Korean
Abstract: Eosinophilic fasciitis (EF) is a relatively rare disorder characterized by eosinophilia of the peripheral blood and inflammation of fascia and skin. The etiology of EF is unknown but it can precede or occur concomitantly with hematologic disorders including malignancy. EF can rarely occur after bone marrow transplantation and is a feature of chronic graft-versus-host disease (cGVHD). We report a 49-year-old man who developed EF as the first manifestation of cGVHD after allogeneic hematopoietic stem cell transplantation (AlloHSCT).