Application of plasma SARS-CoV-2 quantitative antigen detection in the diagnosis and treatment of COVID-19.
10.3760/cma.j.cn112150-20230711-00003
- VernacularTitle:血浆SARS-CoV-2抗原定量检测在COVID-19诊治中的应用
- Author:
Yu Tao SHEN
1
;
Ming GUAN
1
Author Information
1. Department of Laboratory Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
- Publication Type:Journal Article
- MeSH:
Humans;
COVID-19/therapy*;
SARS-CoV-2;
Antigens, Viral;
COVID-19 Testing
- From:
Chinese Journal of Preventive Medicine
2023;57(12):2232-2238
- CountryChina
- Language:Chinese
-
Abstract:
The corona virus disease 2019(COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2), has created an urgent need of scientific and effective biomarkers for the purpose of prevention and control. Currently, commonly employed viral nucleic acids, antibodies, and rapid antigen test detection technologies all exhibit a range of limitations, including restricted applicability, inadequate sensitivity and specificity. Plasma SARS-CoV-2 quantitative antigen, as an emerging biomarker, has garnered significant attention due to its potential clinical value in the diagnosis and management of COVID-19. This article comprehensively analyzes the principles and clinical applications of quantitative detection technology for plasma SARS-CoV-2 antigen. Additionally, it explores the challenges encountered in this field and provides insights into future prospects.
