Investigation and analysis on the detection of IgG antibodies against the rubella virus among rural childbearing-age women in preconception period in Yunnan Province from 2013 to 2019.
10.3760/cma.j.cn112150-20230118-00045
- Author:
Zheng Yuan XIE
1
;
Guang CAO
2
;
Juan Juan CHEN
1
;
Ting Ting CHEN
1
;
Li Juan SUN
1
;
Yi Xiao LI
1
;
Wei Lei ZU
1
;
Jun Jie YE
1
;
Ying Xiong DU
1
;
Zi Gao ZHAO
1
;
Han Feng YE
1
Author Information
1. Population and Family Planning Institute of Yunnan Province/NHC Key Laboratory of Periconception Health Birth in Western China,Kunming 650021,China.
2. Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education,Yunnan University/Yunnan Provincial Center for Research & Development of Natural Products/School of Pharmacy,Yunnan University, Kunming 650500, China.
- Publication Type:Journal Article
- MeSH:
Pregnancy;
Female;
Humans;
Rubella virus;
Immunoglobulin G;
Ethnicity;
Minority Groups;
China;
Rubella/prevention & control*;
Antigens, Viral;
Vaccines
- From:
Chinese Journal of Preventive Medicine
2023;57(12):2134-2139
- CountryChina
- Language:Chinese
-
Abstract:
A study was conducted on rural women of childbearing age aged 20-49 who underwent the National Free Preconception Health Examination Project (NFPHEP)in Yunnan Province from 2013 to 2019. Descriptive analysis was conducted to determine the negative rate of IgG antibodies against the rubella virus and its differences among various socio-demographic characteristics. Among the 1 511 203 study subjects, the negative rate of IgG antibodies against the rubella virus was 24.36%. Only 2.64% of the population had received rubella virus vaccine. The negative rate of IgG antibodies among rural childbearing-age women in the preconception period in Yunnan Province decreased with age and educational level (Ptrend<0.001). The negative rate of IgG antibodies in ethnic minority women of childbearing age in the preconception period (25.19%) was higher than that of Han women (23.88%). Among the 22 ethnic groups with over 1 000 participants, the negative rates of IgG antibodies in women of childbearing age from the Blang (32.85%), Bouyei (31.03%), Zhuang (31.01%), and Miao (30.70%) ethnic groups were higher than those of women from other ethnic groups. Among the 16 states (cities) in Yunnan Province, the negative rate of IgG antibodies in pregnant women of childbearing age in Wenshan Zhuang and Miao Autonomous Prefecture (38.06%) and Lincang City (32.63%) was higher than that in other states (cities). The negative rate of serum IgG antibodies in women who reported having received rubella virus vaccine (18.60%) was lower than that in other non-vaccinated populations (24.52%). The proportion of rural women of childbearing age in Yunnan Province who were susceptible to the rubella virus before pregnancy was still high. It is necessary to promote rubella vaccination among people susceptible to rubella, especially pregnant women, to prevent rubella virus infection and reduce the incidence rate and disease burden of rubella people.
