Vaginal microbiota abnormalities in women with unexplained infertility and its treatment.
10.3760/cma.j.cn112150-20230322-00217
- Author:
Jia Ling HUANG
1
;
Xia WANG
1
;
Fan YU
1
;
Ming Yuan LI
1
;
Yuan Ting TANG
1
Author Information
1. Department of Laboratory Medicine, West China Second University Hospital, Sichuan University/Key Laboratory of Birth Defects and Related Maternal and Child Diseases, Ministry of Education, Chengdu 610041, China.
- Publication Type:Journal Article
- MeSH:
Female;
Humans;
Infertility, Female/microbiology*;
Vagina/microbiology*;
Microbiota
- From:
Chinese Journal of Preventive Medicine
2023;57(11):1813-1819
- CountryChina
- Language:Chinese
-
Abstract:
The vaginal microbiota is a complex and dynamic environment that plays an important role in the healthy reproduction of women. The mechanism of unexplained infertility is not yet clear, and the imbalance and low stability of vaginal microbiota may be related to unexplained infertility. Taking probiotic composite preparations to restore normal vaginal microbiota may be a safe and natural method for treating unexplained infertility. This article reviews the probiotic composite preparations used in the treatment of unexplained infertility both domestically and internationally, including the isolation site of the bacterial species, the use method of the composite preparation, the course of treatment, and the final therapeutic effect, aiming to provide a basis for the clinical application of probiotic composite preparations in the treatment of unexplained infertility.