Evaluation of the effectiveness of the evidence base multi-discipline critical strategies on the temperature and clinical outcomes in very preterm infants.
10.3760/cma.j.cn112150-20220930-00952
- VernacularTitle:围产期多学科关键策略对极早产儿体温及临床结局的效果评价
- Author:
Hong ZHOU
1
;
Yuan WANG
1
;
Rong JU
1
;
Xiao YANG
2
;
Na Na WU
1
;
Jun WANG
1
;
Li Wen DING
1
;
Jie FU
1
;
Xue ZHONG
1
Author Information
1. Department of Neonatology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China.
2. Obstetric, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China.
- Publication Type:Randomized Controlled Trial
- MeSH:
Child;
Female;
Humans;
Infant;
Infant, Newborn;
Fever;
Hypothermia/prevention & control*;
Infant, Premature;
Infant, Very Low Birth Weight;
Temperature
- From:
Chinese Journal of Preventive Medicine
2023;57(8):1266-1270
- CountryChina
- Language:Chinese
-
Abstract:
To evaluate the effectiveness of intervention plans developed by the evidence base multi-discipline critical strategies (EBPCS) on temperature and clinical outcomes in very preterm infants (VPIs) born at<32 weeks. Clinical data were collected from VPIs born in the delivery room/operating room of Chengdu Women's and Children's Central Hospital from May 1, 2021, to May 31, 2022, who required immediate temperature management and were transferred to the neonatal intensive care unit (NICU) of the hospital. The study population was randomly divided into a control group and an intervention group based on the random number table method, with 108 cases in each group. The control group implemented the conventional temperature management recommended by domestic guidelines, while the intervention group adopted EBPCS interventions compared to the control group. The differences in body temperature and clinical outcomes between the two groups were compared after the implementation of different temperature management strategies. A total of 216 VPIs were included. The intervention group had a lower incidence of hypothermia (30.55% vs. 87.03%, P<0.001), higher mean body temperature admitted to the NICU [(36.56±0.31) ℃ vs. (35.77±0.53) ℃, P<0.001], a lower dose of pulmonary surfactant [(115.94±36.96) mg/kg vs. (151.41±54.68) mg/kg, P=0.014], shorter duration of mechanical ventilation [(5.77±1.26) days vs. (14.19±4.63) days, P=0.006], and lower incidence of intraventricular haemorrhage (12.04% vs. 23.15%, P=0.032). The implementation of temperature intervention strategies developed by the EBPCS for VPIs after birth could prevent and reduce the incidence of hypothermia and improve clinical outcomes.
