Value of fecal immunochemical test in colorectal cancer screening.
10.3760/cma.j.cn112152-20230418-00176
- Author:
Yue Yang ZHOU
1
;
Na LI
2
;
Bin LU
2
;
Chen Yu LUO
2
;
Yu Han ZHANG
2
;
Jia Hui LUO
2
;
Ming LU
1
;
Jie CAI
3
;
Min DAI
4
;
Hong Da CHEN
1
Author Information
1. Institute of Clinical Medicine/Translational Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
2. Institute of Clinical Medicine/Translational Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
3. Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
4. National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Fecal immunochemical test;
Screening
- MeSH:
Humans;
Early Detection of Cancer/methods*;
Colonoscopy;
Mass Screening;
Colorectal Neoplasms/pathology*;
Occult Blood
- From:
Chinese Journal of Oncology
2023;45(11):911-918
- CountryChina
- Language:Chinese
-
Abstract:
Screening and early diagnosis and treatment have been proven effective in reducing the incidence and mortality of colorectal cancer. Colonoscopy combined with pathological examination is the gold standard for colorectal cancer screening. However, due to the invasiveness, high cost and the need for professional endoscopists of colonoscopy, it is not feasible to directly use this method for mass population screening. Fecal immunochemical test (FIT) is one of the screening techniques recommended by authoritative international guidelines for colorectal cancer screening, and has been widely used in population-based colorectal cancer screening programs in countries around the world. This paper elaborates on the value of FIT in colorectal cancer screening from different aspects, such as the technical principles, the screening efficiency, the screening strategies, and the population effects and benefits. Additionally, it describes the current situation of colorectal cancer screening in China and summarizes the challenges faced in colorectal cancer screening in order to optimize the FIT-based colorectal cancer screening strategies in the population and provide theoretical reference for effective colorectal cancer screening.
