Research progress of vaccination status, efficacy and safety in children with tumor.
10.3760/cma.j.cn112150-20230213-00101
- Author:
Yu Yang XU
1
;
Qing Hua CHEN
2
;
Yan LIU
1
;
Chai JI
3
;
Jian DU
1
;
Ming Yan LI
3
;
He Ping SHEN
3
;
Xue Chao ZHANG
1
;
Xin Ren CHE
1
;
Gang ZHAO
1
Author Information
1. Department of Expanded Program on Immunization, Hangzhou Center for Disease Control and Prevention, Hangzhou 310021, China.
2. Department of Expanded Program on Immunization, Linping Center for Disease Control and Prevention, Hangzhou 311100, China.
3. Department of Pediatric Health Care, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310000, China.
- Publication Type:Journal Article
- MeSH:
Child;
Humans;
Quality of Life;
Vaccination;
Vaccines;
Neoplasms/prevention & control*;
Communicable Diseases
- From:
Chinese Journal of Preventive Medicine
2024;58(1):87-91
- CountryChina
- Language:Chinese
-
Abstract:
Malignant tumors in children are one of the most important diseases that threaten the health and quality of life of children and are the second most common cause of death in children.With the continuous improvement and progress of treatment technology, the long-term survival rate of children with tumor has been significantly improved, but both the disease itself and the treatment can impair the immune function of children, which makes them vulnerable to various infectious diseases and secondary serious complications, and even become a source of infection, endangering the health of others. Vaccination is the most cost-effective measure to prevent infectious diseases. For children with normal immune functions, the benefits of vaccination usually outweigh the disadvantages. However, there is a lack of detailed data on the vaccination situation, efficacy and safety of vaccine use for such immunocompromised tumor survivors, and there are no authoritative and uniform vaccination recommendations. This article reviewed and summarized the literature and consensus of some domestic and foreign scholars on current status of post-treatment vaccination status, efficacy and safety of vaccination for children with tumors after treatment, with the aim of providing a reference for the practice in this field in China.
