Current status and challenges of long-term safety evaluation of using tests of cosmetics on human body.
10.3760/cma.j.cn112150-20230509-00358
- Author:
Yi Cen YAN
1
;
Hang LI
1
;
Yan TIAN
2
Author Information
1. Department of Dermatology and Venereology, Peking University First Hospital, National Clinical Research Center for Skin and Immune Diseases, National Medical Products Administration Key Laboratory for Quality Control and Evaluation of Cosmetics, Beijing 100034, China.
2. Department of Dermatology, Air Force Medical Center of PLA, Beijing 100142, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Cosmetics;
Human Experimentation
- From:
Chinese Journal of Preventive Medicine
2023;57(12):2220-2223
- CountryChina
- Language:Chinese
-
Abstract:
The use of cosmetics in the crowd has the long-term characteristics. The adverse reactions of cosmetics reported in other country in the world suggest that human patch tests and short-term human using test may not be sufficient to evaluate the safety of high-risk new cosmetic raw ingredients, and long-term human using test should be conducted for evaluation. Therefore, this article reviews the key factors that affect long-term human trial trials, such as site of use, single-use amount, frequency of use, duration of use, and subject conditions, providing supportive evidence for standardized safety evaluation standards for long-term human using test of cosmetics.
