Serologic Test and Therapeutic Drugs of Episcleritis and Scleritis.
- Author:
Dong Youk CHOI
1
;
Myung Kyoo KO
;
Sang Chul BAE
Author Information
1. Department of Ophthalmology, Hanyang University College of Medicine, Korea. fovea@hanyang.ac.kr
- Publication Type:Original Article
- Keywords:
Episcleritis;
Scleritis;
Serology;
Treatment
- MeSH:
Antibodies, Antinuclear;
Humans;
Retrospective Studies;
Rheumatoid Factor;
Scleritis*;
Serologic Tests*
- From:Journal of the Korean Ophthalmological Society
2003;44(7):1496-1503
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate serologic tests and therapeutic drugs of the patients with episcleritis and scleritis. METHODS: Retrospective chart review was performed for above patients that had been followed from 1986. 8. 8 to 2001. 6. 4. RESULTS: Of a total of 26 patients, 5 patients (38.5%) with episcleritis and 7 patients (53.8%) with scleritis showed seropositivity. Rheumatoid factor (RF) (26.1%) and antinuclear antibody (ANA) (26.1%) were most commonly positive. Eleven patients (84.6%) with episcleritis group were given topical steroid, 3 patients (23.1%) were treated with systemic drugs due to ocular lesions, and 6 patients (46.2%) with systemic drug for underlying systemic diseases. In scleritis group, 11 patients (84.6%) were treated with topical steroid, 2 patients (15.4%) with systemic drugs for ocular lesions, and 7 patients (53.8%) with systemic drug for underlying systemic diseases. An average period of treatment time was 6.4 weeks in episcleritis and 11.1 weeks in scleritis. CONCLUSIONS: Serologic tests help document the underlying disorders in patients with scleritis and in those with persistent or often recurred episcleritis. Also treatment of episcleritis and scleritis requires understanding possible effects of systemic drugs adminstered for underlying disorder on ocular lesion, and requires cooperation with internists and rheumatolgists.
