Comparison of 5-year follow-up outcomes between"one-stop"procedure and long-term oral anticoagulants after radiofrequency catheter ablation in patients with atrial fibrillation.
10.3760/cma.j.cn112148-20230622-00368
- Author:
Wei Dong ZHUO
1
;
Guo Hua FU
1
;
Bin Hao WANG
1
;
Bin HE
1
;
Xian Feng DU
1
;
Yi Bo YU
1
;
Ming Jun FENG
1
;
Jing LIU
1
;
Ying Bo QI
1
;
Hui Min CHU
1
Author Information
1. Arrhythmia Center, the First Affiliated Hospital of Ningbo University, Ningbo 315000, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Female;
Middle Aged;
Aged;
Male;
Atrial Fibrillation/surgery*;
Cross-Sectional Studies;
Follow-Up Studies;
Retrospective Studies;
Anticoagulants/therapeutic use*;
Catheter Ablation;
Ischemic Stroke
- From:
Chinese Journal of Cardiology
2023;51(9):951-957
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To compare the 5-year follow-up outcomes of radiofrequency catheter ablation (RFCA) combined with left atrial appendage closure (LAAC) and long-term oral anticoagulant (OAC) after RFCA in patients with atrial fibrillation. Methods: This retrospective cross-sectional study included patients with atrial fibrillation who underwent"one-stop"procedure in the First Affiliated Hospital of Ningbo University from September 2015 to December 2017 (RFCA+LAAC group). Baseline data of patients were collected. Propensity score matching at the ratio of 1∶1 was used to select patients with atrial fibrillation who took long-term OAC after RFCA (RFCA+OAC group). The maintenance rate of sinus rhythm and the incidence of adverse events during follow-up were compared between the two groups. Results: A total of 110 patients were enrolled in the RFCA+LAAC group and RFCA+OAC group, respectively. Age of patients was (67.4±8.8) years in RFCA+LAAC group, and there were 42 (38.2%) female patients. Age of patients was (67.3±7.9) years in RFCA+OAC group, and there were 47 (42.7%) female patients. The patients were followed up for mean of (5.3±1.1) years. There was no significant difference in the maintenance rate of sinus rhythm (log-rank: χ2=0.277, P=0.602) and incidence of ischemic stroke events (2.7% (3/110) vs. 4.5% (5/110), P=0.719) during follow-up between the two groups. The incidence of bleeding events (6.4% (7/110) vs. 18.2% (20/110), P=0.008) and major bleeding events (1.8% (2/110) vs. 8.2% (9/110), P=0.030) was significantly higher in the RFCA+OAC group than in the RFCA+LAAC group. Conclusion: There is no significant difference between RFCA+LAAC group and RFCA+OAC group in maintenance rate of sinus rhythm and incidence of ischemic stroke events. Patients in the RFCA+LAAC group have a lower risk of bleeding events compared to the RFCA+OAC group.
