Relationship between Serum Vitamin E Level and Serum High-Sensitivity C-Reactive Protein in Koreans: Based on National Health and Nutrition Survey
10.21215/kjfp.2020.10.6.456
- Author:
Juntae KIM
1
;
Sunmi KIM
Author Information
1. Department of Family Medicine, Kangwon National University Hospital, Chuncheon, Korea
- Publication Type:Original Article
- From:
Korean Journal of Family Practice
2020;10(6):456-460
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background:Inflammation plays a major role in atherothrombosis, and measuring inflammatory markers such as high-sensitivity C-reactive protein (hs-CRP) may provide a novel method for identifying individuals at high risk of plaque rupture. Atherogenesis results from the oxidation of lipids in low-density lipoprotein (LDL). Vitamin E facilitates the reduction in LDL-oxidation, and increases the antioxidant defense system. Therefore, our study aimed to examine the relationship between vitamin E and hs-CRP levels in Korean adults.
Methods:We used data from the Seventh Korea National Health and Nutrition Examination Survey (2016–2018). The study population included healthy adults aged >20 years. We investigated age, blood pressure, glucose levels, total cholesterol, triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, body mass index, serum vitamin E, and serum hs-CRP levels. We analyzed the relationship between serum vitamin E and serum hs-CRP levels using multiple regression tests.
Results:On statistical analysis, vitamin E levels showed a positive correlation with hs-CRP levels in the female group and the total of the unadjusted model. However, the R 2 value is low. After adjustment for factors that may affect hs-CRP, no significant correlation was observed between serum vitamin E and serum hs-CRP levels.
Conclusion:No significant correlation was observed between serum vitamin E and serum hs-CRP levels. Further research is needed on this topic.
