Impact of an Antimicrobial Stewardship Program on Unnecessary Double Anaerobic Coverage Prescription.
- Author:
Young Joo SONG
1
;
Moonsuk KIM
;
Saemi HUH
;
Junghwa LEE
;
Eunsook LEE
;
Kyoung Ho SONG
;
Eu Suk KIM
;
Hong Bin KIM
Author Information
- Publication Type:Original Article
- Keywords: Antimicrobial stewardship program; Inappropriate prescribing; Anaerobic bacteria
- MeSH: Bacteria, Anaerobic; Communicable Diseases; Computer Communication Networks; Cooperative Behavior; Education; Gyeonggi-do; Humans; Inappropriate Prescribing; Mass Screening; Pharmacists; Prescriptions*; Republic of Korea; Seoul; Tertiary Care Centers
- From:Infection and Chemotherapy 2015;47(2):111-116
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: Co-administration of two or more antimicrobials with anti-anaerobic activity is not recommended except in certain circumstances. We therefore conducted an intervention to reduce unnecessary double anaerobic coverage (DAC) prescription. MATERIALS AND METHODS: The intervention consisted of education using an institutional intranet and prospective audits and feedback provided through collaboration between a pharmacist and an infectious diseases physician in Seoul National University Bundang Hospital, a tertiary hospital in Seongnam, Republic of Korea, in 2013. The study period was 1 year which contained 6 months of pre-intervention period and 6 months of intervention period. To estimate the overall effect of the intervention, we compared the monthly number of patients receiving unnecessary DAC for more than 3 days and the proportion of patients receiving unnecessary DAC for more than 3 days among all patients receiving DAC. RESULTS: The average monthly number of patients receiving unnecessary DAC for more than 3 days after screening decreased by 73.9% in the intervention period from 26.8 to 7.0. Wilcoxon rank sum test revealed there was a significant statistical difference in the monthly number of patients receiving unnecessary DAC for more than 3 days (P = 0.005). The proportion of patients receiving unnecessary DAC for more than 3 days after screening among all patients identified as receiving necessary or unnecessary DAC also decreased by 67.8% in the intervention period from 42.3% to 13.6% (P < 0.001). CONCLUSION: The multidisciplinary antimicrobial stewardship program with combined methods reduced unnecessary DAC prescription successfully.
