A New Ring-opened Azaphilone from a Fungus Talaromyces sp. FB15
- Author:
Tae Yeon KIM
1
;
Changyeol LEE
;
Jin Woo LEE
;
Sang Hee SHIM
Author Information
- From:Natural Product Sciences 2024;30(1):59-63
- CountryRepublic of Korea
- Language:English
- Abstract: Eleven compounds (1–11), including a new azaphilone derivative (1), were isolated from cultures of Talaromyces sp. FB15, a marine fungus collected in the Beaufort Sea in northern Alaska. The structures of the isolated compounds were established by analysis of 1D and 2D NMR data, and they all were turned out to be polyketides such as azaphilone, anthraquinone, and anthrones. Interestingly, the structure of the new metabolite (1) was determined to have an azaphilone scaffold with the pyran ring opened, and to our knowledge, this is the second report on the isolation of this type of azaphilones.
