Study on manufacture of nifedipine tablets with sustained action from carbopol as excipient
- Author:
Hue Minh Pham
- Publication Type:Journal Article
- Keywords:
nifedipine
- MeSH:
Nifedipine;
Excipients
- From:Pharmaceutical Journal
2000;291(7):19-22
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Nifedipine sustained release formulations were made with HPMC, Carbopol, Lycatab, Avicel and magnesi stearat. The effects of the three excipients: HPMC, carbopol, lycatab on the drug release from the formulations were studied. The dissolution profile of a tablet formulation was found to be similar to that of adalat retard 20mg by optimization method and the statistical analysis. This formulation may be used in producing of nifedipine sustained release tablets.
