Medical Treatment of Premenstrual Syndrome.
10.5124/jkma.2005.48.7.672
- Author:
Tak KIM
1
Author Information
1. Department of Obstetrics and Gynecology, Korea University College of Medicine, Ansan Hospital, Korea. tkim@kumc.or.kr
- Publication Type:Original Article
- Keywords:
Premenstrual syndrome;
Treatment
- MeSH:
Anovulation;
Anti-Anxiety Agents;
Antidepressive Agents, Tricyclic;
Complementary Therapies;
Diuretics, Potassium Sparing;
Female;
Gonadotropin-Releasing Hormone;
Life Style;
Neurotransmitter Agents;
Ovulation;
Premenstrual Syndrome*;
Serotonin Uptake Inhibitors
- From:Journal of the Korean Medical Association
2005;48(7):672-678
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The premenstrual syndrome is a common sense one: the cyclic appearance of one or more of a large constellation of symptoms just prior to menses, occuring to such a degree that lifestyle or work is affected, followed by a period of time entirely free of symptoms. Symptoms are believed to the result from interaction between central neurotransmitters and normal menstrual hormonal changes. Pharmacologic management to support efficacy includes selective serotonin reuptake inhibitors administered daily or premenstrually and serotonergic tricyclic antidepressants. Anxiolytics and potassium sparing diuretics have demonstrated mixed results in the literature. Hormonal therapy is available towards producing anovulation. There is a good clinical evidence for GnRH agonist with addback hormonal therapy. Oral contraceptive pills prevent ovulation and should be effective for the treatment of PMS. Treatment usually begins with lifestyle changes, over-thecounter medications. Physicians should be aware of the risks from many alternative therapies commonly touted in the popular press.
