Adult-Onset Still’s Disease with Atypical Persistent Rash and Histologic Findings of Neutrophilic Urticarial Dermatosis
- Author:
Yu Jeong PARK
1
;
Hui Young SHIN
;
Woo Kyoung CHOI
;
Hyun Bo SIM
;
Jong Soo HONG
;
Ai-Young LEE
;
Seung Ho LEE
Author Information
1. Department of Dermatology, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea
- Publication Type:Case Report
- From:Korean Journal of Dermatology
2024;62(1):42-45
- CountryRepublic of Korea
- Language:English
-
Abstract:
Adult-onset Still’s disease (AOSD) is a rare systemic inflammatory disease characterized by spiking fever, arthralgia, skin rashes, and hyperferritinemia. The rash is usually salmon-colored, non-itchy, accompanied by fever, and disappears with an improvement of fever. However, in some cases, the rash persisted regardless of fever. Here, we present a case of AOSD with an atypical persistent rash that showed histological findings resembling those of neutrophilic urticarial dermatosis. The patient was a 60-year-old woman with high fever, arthralgia, and a persistent flagellated skin rash. Despite systemic steroid treatment, the patient developed a serious complication: macrophage activation syndrome. Since this case presented with an atypical persistent rash with histological resemblance to neutrophilic urticarial dermatosis, we report its contribution to the further study of AOSD.
