Evaluation of the Appropriateness of Platelet Transfusions at Two Tertiary Hospitals
10.17945/kjbt.2024.35.1.3 3
- Author:
Yu Been OH
1
;
Ha Jin LIM
;
Yong Jun KWON
;
Yong Jun CHOI
;
Joo-Heon PARK
;
Hyun-Jung CHOI
;
Hyun-Woo CHOI
;
Seung-Jung KEE
;
Eun-Hee NAH
;
Myung-Geun SHIN
;
Jong Hee SHIN
Author Information
1. Department of Laboratory Medicine, Chonnam National University Hospital, Gwangju, Korea
- Publication Type:Original Article
- From:Korean Journal of Blood Transfusion
2024;35(1):33-43
- CountryRepublic of Korea
- Language:EN
-
Abstract:
Background:Appropriate platelet transfusion is essential for patient blood management and allocating limited healthcare resources. Therefore, this study evaluated the appropriateness of platelet transfusion in two tertiary hospitals.
Methods:At Chonnam National University Hospital (Hospital A) and Chonnam National University Hwasun Hospital (Hospital B), 1,470 platelet transfusions (299 and 1,171 cases at Hospitals A and B, respectively) during a single month were reviewed retrospectively using the Korean Transfusion Guidelines (5th edition).
Results:The most common indications were therapeutic transfusion to ensure hemostasis (54.8%) at Hospital A and to prevent spontaneous bleeding in patients with hematologic/oncologic diseases (65.8%) at Hospital B. Overall, 87.3% and 76.3% of transfusions were appropriate at Hospitals A and B, respectively. According to the different transfusion indications, the therapeutic transfusions were appropriate in more than 80% of cases in both hospitals.The appropriateness of prophylactic transfusions against spontaneous bleeding was 80.7% and 69.3%, respectively, and those before surgery or invasive procedures were 72.0% and 66.2%, respectively. Of the 38 and 278 inappropriate transfusions in Hospitals A and B, respectively (as determined by pre-transfusion platelet counts), most cases had platelet counts between 50 and 100×109 /L in Hospital A (23 cases) and between 20 and 50×109 /L in Hospital B (198 cases).
Conclusion:The two hospitals differed in terms of transfusion indications, appropriateness, and cases of inappropriateness. The indications and appropriateness of platelet transfusion should be reviewed in real practice on a hospital-by-hospital basis to improve transfusion management.