Multiple Evanescent White Dot Syndrome following COVID-19 Vaccination: Two Case Reports
10.3341/jkos.2024.65.7.480
- Author:
Han Eul LEE
1
;
Soyeon JUNG
;
Hee Seung CHIN
Author Information
1. Department of Ophthalmology, Inha University Hospital, Inha University School of Medicine, Incheon, Korea
- Publication Type:Case Report
- From:Journal of the Korean Ophthalmological Society
2024;65(7):480-485
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Purpose:We present two cases of multiple evanescent white dot syndrome (MEWDS) following COVID-19 vaccination.Case summary: We present two cases of visual field defects following BNT162b2 (Pfizer-BioNTech, Kronach, Germany) COVID-19 vaccination. A 14-year-old male experienced reduced visual acuity in the temporal field of his left eye after his second dose. Similarly, a 38-year-old woman experienced decreased visual acuity in her right eye after her first dose. Notably, neither patient had pre-existing medical conditions or exhibited COVID-19 symptoms following vaccination. Funduscopic examination revealed multifocal peripapillary hyperreflective lesions in both cases. Visual field defects and hyperreflective lesions spontaneously resolved within 6 weeks, with normal visual acuity and fundus findings at the 7-month follow-up.
Conclusions:The recent COVID-19 pandemic has led to a significant increase in vaccination rates. Notably, MEWDS demonstrated a significant association with previous vaccines, including influenza and hepatitis, and the cases describe herein also suggest a potential association between BNT162b2 vaccination and MEWDS.
