Cerebral Amyloid Angiopathy: An Undeniable Small Vessel Disease

Author: Litao WANG ¹ ; Qiong LIU ; Dongqi YUE ; Jun LIU ; Yi FU
Author Information

1. Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Publication Type:Review
From:Journal of Stroke 2024;26(1):1-12
CountryRepublic of Korea
Language:English
Abstract: Cerebral amyloid angiopathy (CAA) has been proven to be the most common pathological change in cerebral small vessel disease except arteriosclerosis. In recent years, with the discovery of imaging technology and new imaging markers, the diagnostic rate of CAA has greatly improved. CAA plays an important role in non-hypertensive cerebral hemorrhage and cognitive decline. This review comprehensively describes the etiology, epidemiology, pathophysiological mechanisms, clinical features, imaging manifestations, imaging markers, diagnostic criteria, and treatment of CAA to facilitate its diagnosis and treatment and reduce mortality.