A rare goblet cell adenocarcinoma arising from Barrett’s esophagus: the first reported case in the esophagus
- Author:
Chi Eun OH
1
;
Sung Eun KIM
;
Sun-Ju OH
Author Information
- Publication Type:Case Study
- From:Journal of Pathology and Translational Medicine 2024;58(2):81-86
- CountryRepublic of Korea
- Language:EN
- Abstract: Goblet cell adenocarcinoma (GCA) is a rare and distinctive amphicrine tumor comprised of goblet-like mucinous cells and neuroendocrine cells. It is believed to originate from pluripotent stem cells located at the base of crypts. GCA predominantly arises from the appendix, with a few reported cases in extra-appendiceal locations such as the colorectum, small intestine, and stomach. In this case report, we present a unique instance of a 64-year-old male who initially received a diagnosis of neuroendocrine carcinoma in the distal esophagus based on biopsy but, following resection, was subsequently re-diagnosed with GCA arising from Barrett’s esophagus.
