Factors Associated With the Prevalence of Irritable Bowel Syndrome: The Miyagi Part of the Tohoku Medical Megabank Project Community-based Cohort Study
- Author:
Kumi NAKAYA
1
;
Naoki NAKAYA
;
Mana KOGURE
;
Rieko HATANAKA
;
Ippei CHIBA
;
Ikumi KANNO
;
Satoshi NAGAIE
;
Tomohiro NAKAMURA
;
Motoyori KANAZAWA
;
Soichi OGISHIMA
;
Nobuo FUSE
;
Shin FUKUDO
;
Atsushi HOZAWA
Author Information
- Publication Type:Original Article
- From:Journal of Neurogastroenterology and Motility 2024;30(2):208-219
- CountryRepublic of Korea
- Language:EN
-
Abstract:
Background/Aims:The objective of this research is to examine factors related to irritable bowel syndrome (IBS) prevalence in a large population-based study.
Methods:A cross-sectional study was conducted with participants in the Miyagi part of the Tohoku Medical Megabank Project CommunityBased cohort study who completed the Rome II Modular Questionnaire. Multivariate odds ratios (ORs) for the presence of IBS and 95% confidence intervals (95% CIs) for the reference group were calculated for each factor. Additionally, a stratified analysis was performed by sex and age group (20-49 years, 50-64 years, and ≥ 65 years).
Results:Among 16 252 participants, 3025 (18.6%) had IBS, comprising 750 men (15.5%) and 2275 women (19.9%). Multivariate ORs for the presence of IBS decreased significantly with each year of age (OR, 0.98; 95% CI, 0.98-0.99). Moreover, compared with the reference group, ORs for the presence of IBS were significantly higher in individuals whose home was partially damaged by the Great East Japan Earthquake, those with < 16 years of education, those who spent less time walking, those with high perceived stress (1.77, 1.57-2.01), those with high psychological distress (1.58, 1.36-1.82), and those with high symptoms of depression (1.76, 1.60-1.94). In stratified analyses, a significant relationship was found between psychological factors and IBS prevalence in all sex and age groups.
Conclusions:This large cross-sectional population-based cohort study identified several factors associated with IBS prevalence. Psychological factors were significantly associated with IBS prevalence across all age groups and sexes.
