Protein S Deficiency Presenting as Severe Peripheral Arterial Insufficiency.
- Author:
Yong Pil CHO
1
;
Gil Hyun KANG
;
Myoung Sik HAN
;
Hyuk Jai JANG
;
Yong Ho KIM
;
Youn Baik CHOI
Author Information
1. Department of Surgery, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea. ypcho@gnah.co.kr
- Publication Type:Case Report
- Keywords:
Arterial occlusion;
Protein S;
Deficiency
- MeSH:
Female;
Humans;
Incidence;
Natural History;
Protein C;
Protein S Deficiency*;
Protein S*;
Thrombosis
- From:Journal of the Korean Society for Vascular Surgery
2004;20(1):142-145
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Among the numerous conditions that can lead to a hypercoagulable state, protein C and S deficiencies have been frequently described. Although protein C and S deficiencies have frequently been associated with venous thromboembolic events, instances of arterial thromboses have been reported, especially in young patients. The exact incidence of protein C and S deficiencies in patients with peripheral arterial insufficiency has not been established. Given the paucity of adequate studies to define the natural history and arteriographic findings of these patients, treatment has not been well delineated. We report a young female patient who presented with severe peripheral arterial insufficiency and underwent an unusual clinical course associated with protein S deficiency.
