Skull Metastasis of Gastric Gastrointestinal Stromal Tumor Successfully Managed by Surgery.
10.3340/jkns.2014.0506.007
- Author:
Inkeun PARK
1
;
Dong Hae CHUNG
;
Chan Jong YOO
;
Dong Bok SHIN
Author Information
1. Division of Hematology-Oncology, Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea. dbs@gilhospital.com
- Publication Type:Case Report
- Keywords:
Gastrointestinal stromal tumor;
Skull metastasis;
Metastasectomy;
Target therapy;
Multidisciplinary treatment
- MeSH:
Gastrointestinal Stromal Tumors*;
Gastrointestinal Tract;
Humans;
Imatinib Mesylate;
Liver;
Metastasectomy;
Neoplasm Metastasis*;
Peritoneum;
Pneumonia;
Recurrence;
Sepsis;
Skull*
- From:Journal of Korean Neurosurgical Society
2017;60(1):94-97
- CountryRepublic of Korea
- Language:English
-
Abstract:
Gastrointestinal stromal tumors (GISTs) are rare, but are the most common mesenchymal neoplasm of the gastrointestinal tract. The most common sites of metastasis are liver and peritoneum, while bone metastasis is rare. We report on a patient with skull metastasis after seven years of treatment with imatinib for metastatic GIST. She underwent metastasectomy consisting of craniectomy with excision of the mass, and cranioplasty and continued treatment with imatinib and sunitinib, without evidence of cranial recurrence. She died of pneumonia sepsis one year after metastasectomy. Skull metastasis of GIST is a very rare presentation, and an aggressive multidisciplinary approach should be considered whenever possible.
