SoUth Korean study to PrEvent cognitive impaiRment and protect BRAIN health through Multidomain interventions via facE-to-facE and video communication plaTforms in mild cognitive impairment (SUPERBRAIN-MEET): Protocol for a Multicenter Randomized Controlled Trial
10.12779/dnd.2024.23.1.30
- Author:
Soo Hyun CHO
1
;
Hae Jin KANG
;
Yoo Kyoung PARK
;
So Young MOON
;
Chang Hyung HONG
;
Hae Ri NA
;
Hong-Sun SONG
;
Muncheong CHOI
;
Sooin JEONG
;
Kyung Won PARK
;
Hyun Sook KIM
;
Buong-O CHUN
;
Jiwoo JUNG
;
Jee Hyang JEONG
;
Seong Hye CHOI
Author Information
1. Department of Neurology, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, Korea
- Publication Type:Original Article
- From:Dementia and Neurocognitive Disorders
2024;23(1):30-43
- CountryRepublic of Korea
- Language:EN
-
Abstract:
Background:and Purpose: The SoUth Korea study to PrEvent cognitive impaiRment and protect BRAIN health through lifestyle intervention (SUPERBRAIN) proved the feasibility of multidomain intervention for elderly people. One-quarter of the Korean population over 65 years of age has mild cognitive impairment (MCI). Digital health interventions may be costeffective and have fewer spatial constraints. We aim to examine the efficacy of a multidomain intervention through both face-to-face interactions and video communication platforms using a tablet personal computer (PC) application in MCI.
Methods:Three hundred participants aged 60–85 years, with MCI and at least one modifiable dementia risk factor, will be recruited from 17 centers and randomly assigned in a 1:1 ratio to the multidomain intervention and the waiting-list control groups. Participants will receive the 24-week intervention through the tablet PC SUPERBRAIN application, which encompasses the following five elements: managing metabolic and vascular risk factors, cognitive training,physical exercise, nutritional guidance, and boosting motivation. Participants will attend the interventions at a facility every 1–2 weeks. They will also engage in one or two self-administered cognitive training sessions utilizing the tablet PC application at home each week. They will participate in twice or thrice weekly online exercise sessions at home via the ZOOM platform. The primary outcome will be the change in the total scale index score of the Repeatable Battery for the Assessment of Neuropsychological Status from baseline to study end.
Conclusions:This study will inform the effectiveness of a comprehensive multidomain intervention utilizing digital technologies in MCI.
