Prevalent morphometric vertebral fractures as a risk factor for subsequent clinical vertebral fractures after shortfusion surgery in older Japanese women with degenerative spondylolisthesis
- Author:
Yosuke OISHI
1
;
Eiichiro NAKAMURA
;
Keiji MURAMATSU
;
Masaaki MURASE
;
Katsumi DOI
;
Yoshinori TAKEUCHI
;
Jun-ichi HAMAWAKI
;
Akinori SAKAI
Author Information
- Publication Type:Clinical Study
- From:Asian Spine Journal 2024;18(3):435-443
- CountryRepublic of Korea
- Language:EN
-
Abstract:
Methods:The study enrolled a total of 237 older female patients: 50 and 187 patients had prevalent morphometric VFs (VF [+] group) and nonprevalent morphometric VFs (VF [−] group), respectively. The time to subsequent clinical VFs after fusion surgery was compared between the two groups using the Kaplan-Meier method. Moreover, 40 and 80 patients in the VF (+) and VF (−) groups, respectively, were analyzed and matched by propensity scores for age, follow-up duration, surgical procedure, number of fused segments, body mass index, and number of patients treated for osteoporosis.
Results:Kaplan-Meier analysis indicated that the VF (+) group had a higher incidence of subsequent clinical VFs than the VF (−) group, and Cox regression analysis showed that the presence of prevalent morphometric VFs was an independent risk factor for subsequent clinical VFs before matching. Kaplan-Meier analysis demonstrated comparable results after matching.
Conclusions:The presence of prevalent morphometric VFs may be a risk factor for subsequent clinical VFs in older women with degenerative spondylolisthesis who underwent short-fusion surgery.