Effect of Furosemide on Prevertebral Soft Tissue Swelling after Anterior Cervical Fusion: A Comparative Study with Dexamethasone
- Author:
Ju-Sung JANG
1
;
Young-Seok LEE
;
Myeong Jin KO
;
Seong Hyun WUI
;
Kwang-Sup SONG
;
Seung Won PARK
Author Information
- Publication Type:Clinical Study
- From:Asian Spine Journal 2024;18(1):66-72
- CountryRepublic of Korea
- Language:English
-
Abstract:
Methods:The symptomatic PSTS group received intravenous (IV) administration of dexamethasone or furosemide. The asymptomatic PSTS group did not receive any medication. Patients were divided into the control (no medication, n=31), Dexa (IV dexamethasone, n=25), and Furo (IV furosemide, n=28) groups. PSTS was checked daily with simple radiographs and medication-induced reductions in PSTS from its peak or after medication.
Results:The peak time (postoperative days) of PSTS in the control (2.27±0.47, p<0.05) and Dexa (1.91±0.54, p<0.01) groups were significantly later than that in the Furo group (1.38±0.74). PSTS was significantly lower in the Furo group than in the Dexa group from postoperative days 4 to 7 (p<0.05). PSTS reduction after the peak was significantly greater in the Furo group than in the control (p<0.01) and Dexa (p<0.01) groups. After starting the medication therapy, the Furo group showed a significantly greater reduction in PSTS than the Dexa group (p<0.01). No difference was found in symptom improvement among the three groups.
Conclusions:If furosemide is used to reduce PSTS after ACF, it can effectively reduce symptoms.
