Histopathologic findings of necrotizing lymphadenitis.
10.12701/yujm.1993.10.2.485
- Author:
Young Ran SHIM
;
Hae Joo NAM
- Publication Type:Original Article
- MeSH:
Asian Continental Ancestry Group;
Biopsy;
Fever;
Histiocytes;
Humans;
Lymph Nodes;
Lymphadenitis*;
Lymphatic Diseases;
Lymphocytes;
Lymphoma;
Neutrophils;
Plasma Cells;
Young Adult
- From:Yeungnam University Journal of Medicine
1993;10(2):485-492
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Necrotizing lymphadenitis was first recognised as a self-limiting lymphadenitis by Japanese workers in 1972. It is a distinct clinicopathologic entity, but can be mistaken as malignant lymphoma. We have studied clinicopathologic features in 15 cases of necrotizing lymphadenitis. This disease occurs predominantly in young adult. Male-female ratio is 2 : 1. The commonest presentation is lateral cervical lymphadenopathy. Pain, tenderness, and fever can be seen. Biopsy of the lymph nodes from all patients demonstrates the characteristic histologic features : multifocal, relatively circumscribed nodules in the cortex and/or paracortex, consisting of a mixture of activated large lymphoid cells, histiocytes and Small lymphocytes. Numerous karyorrhetic debris are present. Neutrophils and plasma cells are strikingly absent.
