Effect of romosozumab in premenopausal women with severe osteoporosis and anorexia nervosa
10.1016/j.afos.2023.10.001
- Author:
Kazuki FUJIMOTO
1
;
Narumi MAKI
;
Daisuke HASHIBA
;
Toshifumi MAEYAMA
;
Ryosuke NAKAGAWA
;
Hajime ARAI
;
Seiji OHTORI
Author Information
1. Department of Orthopaedic Surgery, Kohnodai Hospital, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa City, Chiba, 272-8516, Japan
- Publication Type:Original article
- From:Osteoporosis and Sarcopenia
2023;9(4):137-141
- CountryRepublic of Korea
- Language:English
-
Abstract:
Objectives:This study aims to investigate the effects of romosozumab on bone mineral density (BMD) and bone metabolism.
Methods:In this retrospective case series, romosozumab was administered to 5 premenopausal female patients with osteoporosis and anorexia nervosa with fragility fractures. BMD and bone turnover marker changes were investigated at 6 months and 1 year after administering romosozumab.
Results:BMD increased and high-turnover bone metabolism decreased 6 months and 1 year after administering romosozumab.
Conclusions:Romosozumab is useful for treating osteoporosis in patients with anorexia nervosa.
