Lipofibromatosis: A Case Report.
- Author:
Tae Eun KIM
1
;
Tae Jung KIM
;
Youn Soo LEE
;
Chang Suk KANG
;
Sang In SHIM
;
Kyo Young LEE
Author Information
1. Department of Hospital Pathology, The Catholic University of Korea School of Medicine, Seoul, Korea. kimecho@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Fibroma;
Thigh;
Adolescent;
Adipose tissue;
Lipoma
- MeSH:
Actins;
Adipose Tissue;
Adolescent;
Fibroblasts;
Fibroma;
Humans;
Lipoma;
Magnetic Resonance Imaging;
Male;
Thigh;
Young Adult
- From:Korean Journal of Pathology
2011;45(1):106-110
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lipofibromatosis is a recently described rare benign fibrofatty tumor of childhood. It typically forms as an ill defined, slowly growing, painless mass. We present here the case of lipofibromatosis that occurred in a 21-year-old male who had complained of a bulging enlarged mass involving the right thigh and prepatella area for the previous 1 year. Magnetic resonance imaging showed an ill-defined reticular infiltration in the subcutaneous layer with subtle linear enhancement and high T2 signal intensity. The mass was surgically excised and it displayed an 11.0x5.5x1.5 cm-sized adipose appearance without encapsulation. Microscopically, the tumor was composed of alternating streaks of mature adipose tissue and a fibroblastic component that mainly involved the septa of adipose tissue. On immunohistochemical study, the fibroblastic component was positive for S-100, CD99, CD34, actin and bcl-2. He has shown an eventful recovery for 6 months after surgery.
